@font-face {

    font-family: 'Work Sans-Regular';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-Regular.ttf') format('truetype');
}

@font-face {
    font-family: 'Work Sans-SemiBold';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-SemiBold.ttf') format('truetype');
}

@font-face {
    font-family: 'Work Sans-Light';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-Light.ttf') format('truetype');
}

@font-face {
    font-family: 'Work Sans-Bold';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-Bold.ttf') format('truetype');
}
@font-face {
    font-family: 'Work Sans-ExtraBold';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-ExtraBold.ttf') format('truetype');
}

@font-face {
    font-family: 'Work Sans-Medium';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-Medium.ttf') format('truetype');
}

@font-face {
    font-family: 'Work Sans-Italic';
    /* Name for your custom font */
    src: url('../fonts/WorkSans-Italic.ttf') format('truetype');
}

@font-face {

    font-family: 'Arial-bold';
    /* Name for your custom font */
    src: url('../fonts/Arial-bold.ttf') format('truetype');
}

@font-face {

    font-family: 'Arial-Regular';
    /* Name for your custom font */
    src: url('../fonts/Arial-regular.ttf') format('truetype');
}

sup.super-heading {
    font-size: 0.55rem !important;
    top: -0.7rem !important;
}

.bookmark.mobile,
.Us-healthcare.text-white.mobile,
.t_des {
    display: none;
}

p.bookmark {
    font-size: 17px;
    font-family: Work Sans-SemiBold, sans-serif;
    line-height: 14px;
    color: #FFFFFF;
    margin-left: 6px;
    margin-bottom: 0;
}

.bookmark.dekstop {
    margin-left: 3%;
    display: flex;
    align-items: center;
}

a.md {
    color: #ffffff;
}

.space-req {
    white-space: nowrap;
}

p.WAPI {
    margin-bottom: 0px;
    line-height: 28px;
    color: #2D2927;
}
p.infection, p.PEFT, p.IBD, p.HR{
    margin-bottom: 0;
    line-height: 21px;
    color: #2D2927;
}

a.md:hover {
    color: #ffffff;
}

.bg-brand {
    background-color: #582c5f;
}

em {
    font-family: Work Sans-Italic, sans-serif !important;
}

.ar_bold {
    font-size: 17px;
    line-height: 24px;
    font-family: Arial-bold, sans-serif;
}

.none {
    display: none;
}

p {
    font-family: Work Sans-Regular, sans-serif;
    font-size: 14px;
}

.text-white {
    color: #ffffff !important;
}

.bg-pink {
    background-color: #FCF9F9;
    padding: 2% 3% 2% 3%;
}

.arrow_ic {
    display: none;
}

.last_paragraph {
    font-size: 12px;
    font-family: Work Sans-Regular, sans-serif;
}

.text_pink {
    color: #e50f63;
}

.ar_bold.warnings-text {
    line-height: 28px;
}

p.ISIC {
    margin-bottom: 10px;
}

.text_purple {
    color: #582c5f;
}

.text_eighteen {
    font-size: 18px;
    font-family: Work Sans-Medium, sans-serif;
}

.text_fourteen {
    font-size: 14px;
    font-family: Work Sans-SemiBold, sans-serif;
}

.white_border {
    border-left: 1px solid white;
}

p.indication {
    margin-bottom: 9px;
}

li.nav-item.sp {
    display: flex;
    min-width: 100px;
}
.nwarap{
        text-wrap: nowrap;
}
span.nav_sp,
span.nav_spp {
    margin-top: 4%;
    margin-left: 8px;
    border: 0.1px solid white;
    height: 61%;
}

span.nav_spp {
    margin-top: 6%;
    height: 65%;
}

.black_border {
    border-left: 1px solid black;
}

.text_black {
    color: #2D2927;
    ;
}

.Bookmark.text-white,
.Us-healthcare.text-white {
    margin-right: 8%;
    font-size: 12px;
    line-height: 15px;
    font-family: Arial-Regular, sans-serif;
}

.underline {
    text-decoration: underline;
}

a:hover {
    color: #2D2927;
}

.banner-image img {
    width: 100%;
}

.top-banner-mobile-image {
    display: none;
}
/* j_code */
/* .j_ref{font-size: 13px;
    line-height: 18px;
    color: #2D2927;
    text-decoration: none;
} */
/* p.j_ref.sec {
    margin-bottom: 1%;
} */
p.effective_jcode {
    font-size: 27px;
    font-family: 'Work Sans-Regular';
}
.icon_i {
    margin-top: 3%;
    margin-right: 3%;
}
.bt_d {
    margin-bottom: 0%;
}
span.july{
    font-size: 27px;
    font-family: 'Work Sans-Bold'; 
}
p.para_jcode {
    text-align: center;
    
}
.ext-pd {
    padding-top: 5px;
}
.ext-pd-lf{
    padding-left: 5px;   
}
p.parmanent_jcode {
    font-size: 31px;
    font-family: 'Work Sans-Regular';
}

/* .j_code_text.j_Dekstop {
    margin-top: 1.5%;
} */
span.jc.text_pink {
    font-size: 31px;
    font-family: 'Work Sans-ExtraBold';
}
/* .j_code_text.j_mobile {
    display: none;
} */
span.supp {
    margin-left: -6px;
}
/* Header */
.h_image {
    background: linear-gradient(90deg, #e50f63, #582c5f);
    padding-bottom: 2px;
    padding-top: 1%;
}
/* .j_code_text {
    margin: 0 auto;
    width: 100%;
} */
.header_logo {
    padding-top: 5px;
}

.h_imageM {

    background: linear-gradient(90deg, #e50f63, #582c5f);

    padding-bottom: 1.5%;
    padding-top: 1%;
}

span.border_sp {
    margin-top: 10px;
    border: 1px solid #FFFFFF;
    height: 118px;
    margin-right: 5%;
}

.twelve-resolution {
    display: none;
}

p.header_main_para {
    font-size: 55px;
    color: #ffffff;
    font-family: Work Sans-Light, sans-serif;
    padding-left: 12px;
}

.header_content_logo {
    padding-top: 2%;
}

p.header_para {
    margin-top: -2%;
    text-align: center;
    /* width: 87%; */
    font-size: 22px;
    line-height: 20px;
    font-family: Work Sans-Regular, sans-serif;
    color: #ffffff;
}

.first_only {
    font-family: Work Sans-Bold, sans-serif;
}

.header_image {

    display: flex;

}

.header_content {
    display: flex;
}

span.patient {
    font-size: 20px;
}
.location-iconText{
    display: flex;
    margin-bottom: 3%;
}
.locationText {
    margin: 1% 0 1% 2%;
}
.instructional_video .it_video iframe {
    width: 184px;
    height: 140px;
    border: 2px solid black;
}
.instructional_video .it_text {
    padding-right: 32px;
}

/* navbar */
@media only screen and (min-width: 991px) {
    .navbar-expand-lg .navbar-collapse {
        font-size: 12px;
        line-height: 15px;
        font-family: Arial-Regular, sans-serif;
    }

    .navbar-expand-lg .navbar-nav .nav-link {
        white-space: nowrap;
    }

    .navbar-expand-lg .navbar-nav {
        width: 100%;
        justify-content: flex-end;
    }

    .last {
        display: none;
    }

    .header_dekstop {
        display: block;

    }

    .header_Mobile {
        display: none;
    }

}

@media only screen and (max-width: 991px) {

    /* .j_code_text.j_mobile {
        display: block;
        margin-top: 11%;
        width: 100%;
        line-height: 1.2;
    } */
    /* .j_code_text.j_Dekstop{
        display:none;
    } */
    span.nav_sp,
    span.nav_spp {
        display: none;
    }

    .input-wrap input {
        max-width: 45px !important;
    }

    .navbar-toggler {
        width: 20px;
        height: 100%;
        position: relative;
        transition: .5s ease-in-out;
    }

    .last {
        display: block;
    }

    .bg-brand {
        background-color: #582c5f;
        padding-bottom: 2%;
        background-size: 100%;
    }

    header.height--fixed {
        height: 100%;
        left: 0;
        right: 0;
        overflow-y: auto;
    }

    li.nav-item {
        padding-top: 4%;
        display: flex;
        padding-bottom: 7%;
        border-bottom: 1px solid white;
    }

    li.nav-item.lastli {
        border-bottom: none !important;
    }

    .navbar-toggler,
    .navbar-toggler:focus,
    .navbar-toggler:active,
    .navbar-toggler-icon:focus {
        outline: none;
        box-shadow: none;
        border: 0;
    }

    .navbar-toggler span {
        margin: 0;
        padding: 0;
    }

    .toggler-icon {
        display: block;
        position: absolute;
        height: 3px;
        width: 100%;
        background: white;
        border-radius: 1px;
        opacity: 1;
        left: 0;
        transform: rotate(0deg);
        transition: .25s ease-in-out;
    }

    .middle-bar {
        margin-top: 0px;
    }

    /* when navigation is clicked */

    .navbar-toggler .top-bar {
        margin-top: 0px;
        transform: rotate(135deg);
    }

    .navbar-toggler .middle-bar {
        opacity: 0;
        filter: alpha(opacity=0);
    }

    .navbar-toggler .bottom-bar {
        margin-top: 0px;
        transform: rotate(-135deg);
    }

    /* State when the navbar is collapsed */

    .navbar-toggler.collapsed .top-bar {
        margin-top: -20px;
        transform: rotate(0deg);
    }

    .navbar-toggler.collapsed .middle-bar {
        opacity: 1;
        filter: alpha(opacity=100);
    }

    .navbar-toggler.collapsed .bottom-bar {
        margin-top: 20px;
        transform: rotate(0deg);
    }

    /* Color of 3 lines */

    .navbar-toggler.collapsed .toggler-icon {
        background: white;
    }
}

/* Three links css */
.three-links {
    padding-top: 2%;
    margin-bottom: 40px;
}

img.arrow_icon_image {
    margin-top: -8px;
}

li.DAI-links-li {
    padding: 0.5% 5% 0.5% 5%;
    text-align: center;
    background-color: #FCF9F9;
}

ul.DAI-links {
    padding: 0;
    display: flex;
    max-width: 100%;
    list-style-type: none;
    justify-content: space-between;
}

a.DAI-links-li-a {
    text-decoration: none;
    color: #582c5f;
    /* font-weight: 600; */
    font-family: Work Sans-Medium, sans-serif;
    font-size: 14px;
    line-height: 15px;
}

.DAI-links::marker {
    display: none;
}

/* Scrollbar styles */
.myBox {
    background-color: #FCF9F9;
    color: #2D2927;
    border: none;
    padding: 5%;
    width: 100%;
    height: 730px;
    overflow: auto;
}

.rightbar p {
    font-size: 14px;
    line-height: 21px;
    font-family: Arial-Regular, sans-serif !important;
}

.myBox::-webkit-scrollbar {
    width: 12px;
    height: 12px;
}

.myBox::-webkit-scrollbar-track {
    border-radius: 10px;
}

.myBox::-webkit-scrollbar-thumb {
    background: gray;
    border-radius: 10px;
}

.myBox::-webkit-scrollbar-thumb:hover {
    background: gray;
}

/* Calculation steps */
.calculation_steps {
    padding: 2% 3% 2% 3%;
    background-color: #FCF9F9;
    margin-top: 4%;
    color: #000000D9;
}

sup.r-ball {
    top: -7px;
}

.mobile-single-use {
    display: none;
}

input::-webkit-outer-spin-button,
input::-webkit-inner-spin-button {
    -webkit-appearance: none;
    margin: 0;
}

p.three_steps {
    font-size: 20px;
    font-family: Work Sans-SemiBold, sans-serif;
    color: #582c5f;
}

span.cal-first-para-num {
    padding: 1px 7px 1px 7px;
    color: white;
    font-size: 14px;
    font-family: Work Sans-SemiBold, sans-serif;
    margin-right: 1.5%;
    font-weight: 700;
    height: 1%;
    background-color: #e50f63;
    border-radius: 50%;
}

.num-para {
    display: flex;
    line-height: 20px;
}

p.banner-paper {
    line-height: 20px;
    margin-bottom: 0.6rem;
}

p.cal-first-para {
    margin-bottom: 0.9rem;
}

/* Doising Informtion */
.icon-text-main {
    display: flex;
    justify-content: center;
}

p.consentex-solution {
    font-size: 15px;
}

p.doising_information_l_para sup,
p.small_text sup {
    margin-left: -6px;
}

.supper {
    font-family: Work Sans-Regular, sans-serif;
}

.supper.one {
    font-size: .90rem;
}

p.doising_information_pr.text_pink {
    font-size: 19px;
    margin-bottom: 5px;
}

p.doising_information_l_para {
    font-size: 13px;
    color: #2D2927;
}

.icon-text {
    /* width: 35%; */
    padding-left: 4%;
    margin-bottom: 3%;
    margin-top: 2%;
    display: flex;
}
.no-underline {
    text-decoration: none;
}

.pr {
    margin-top: -8px;
    width: 105%;
    font-family: Arial-Regular, sans-serif;
}

p.mg_pr {
    margin: -10% 0 0 0;
    font-size: 16px;
    font-family: Work Sans-Medium, sans-serif;
}

span.mg.text_purple {
    font-size: 50px;
    font-family: Work Sans-Bold, sans-serif;
}

/* instructional_video */
.IV {
    margin-top: 4%;
}

.video_heading {
    font-size: 16px;
    font-family: Work Sans-SemiBold, sans-serif;
}

.instructional_video .transcript-text{
    color: #000000D9;
    font-weight: bold;
}

.instructional_video {
    display: flex;
    padding: 2% 0 2% 0;
    z-index: 1;
    position: relative;

}

.IV {
    margin-top: 4%;
}

.last_paragraph {
    padding: 2%;
    margin-top: 2%;

}

.instructional_video:before,
.instructional_video:after {
    background: #FCF9F9 !important;
}

.instructional_video:before {
    position: absolute;
    /* top: -10px; */
    top: -7px;
    left: 3%;
    content: "";
    display: block;
    height: 10px;
    width: 93%;
    background: white;
}

.instructional_video:after {
    position: absolute;
    /* bottom: -10px; */
    bottom: -7px;
    left: 3%;
    content: "";
    display: block;
    height: 10px;
    width: 93%;
    background: white;
}

p.last_p1 {
    font-size: 13px;
    line-height: 18px;
    color: #2D2927;
}

p.last_p1.calc-astrik {
    font-size: 13px;
    line-height: 18px;
    color: white;
    padding: 0px 5% 24px 5%;
}
p.last_p1.calc-astrik .supp {
    margin-left: -6px;
}

.work-it {
    font-family: Work Sans-Italic, sans-serif;
}

.References {
    font-family: Work Sans-SemiBold, sans-serif;
}

/* accordian */
ul.step-ul {
    line-height: 20px;
}

ul.step-ul.discard {
    margin-bottom: 0;
}

ul.inside-ul {
    list-style: none;
}

ul.inside-ul>li:before {
    content: '\2013';
    position: absolute;
    margin-left: -20px;
    font-weight: bolder;
    color: #e50f63;
}

li.stepul-li {
    margin-bottom: 2%;
    margin-top: -5px;
}

.lineheight {
    line-height: 20px;
}

li.step2-d {
    margin-bottom: 2%;
}

label.accordion {
    display: block;
    padding: 8px 22px;
    margin: 15px 0 1px 0;
    cursor: pointer;
    background: linear-gradient(90deg, #e50f63, #582c5f);
    border-radius: 23px;
    color: #FFF;
    font-size: 18px;
    font-family: Work Sans-SemiBold, sans-serif;
    transition: ease .5s;
    position: relative;
}

.step_paragraph ul li {
    font-size: 14px;
    margin-bottom: 9px;
    font-family: Work Sans-Regular, sans-serif;
}

.heading-tr {
    background: linear-gradient(90deg, #e50f63, #582c5f);
}

/* label.accordion::after {
    content: '+';
    font-size: 22px;
    font-weight: bold;
    position: absolute;
    right: 10px;
    top: 2px;
} */
label.accordion::after {
    content: '+';
    font-size: 16px;
    line-height: 1;
    padding-top: 1px;
    font-weight: bold;
    text-align: center;
    position: absolute;
    right: 24px;
    margin-top: 3px;
    display: inline-block;
    color: #e50f63;
    background: #fff;
    height: 18px;
    width: 18px;
    border-radius: 2px;
}

input#title1:checked+label.accordion::after {
    content: '-';
    padding-top: 0;
    /* right: 14px;
    top: 3px; */
}

input#title1:checked+label.accordion {
    border-radius: 21px 21px 0 0;
}

.content {

    padding: 10px 25px;
    margin: 0 0 1px 0;
    border-radius: 3px;
}

input#title1+label.accordion+.content {
    display: none;
}

input#title1:checked+label.accordion+.content {
    display: block;
    padding-top: 3%;
}

input#title1 {
    display: none;
}

/* accordian content*/

.step_icon_heading {
    display: flex;
}

.step_heading {
    margin-left: 2%;
    margin-top: 1%;
    font-size: 18px;
}

.step_heading p.text_pink {
    margin-bottom: -3px;

}

.step-ul li::marker {
    color: #e50f63;
}

tr:nth-child(odd) {
    background-color: #EAE4EA;

}

tr.gray_tr td {
    padding: 1% 2% 1% 3% !important;
}

table.dosing-table th {
    /* background: linear-gradient(90deg, #d60e63, #5b235d); */
    color: white;
    padding: 1% 2% 1% 3%;
    font-size: 12px;
    font-family: Work Sans-SemiBold, sans-serif;
}

table.dosing-table {
    width: 100%;
}

table.dosing-table td {
    padding: 2% 2% 2% 3%;
    line-height: 20px;
    color: #000000;
    font-size: 12px;
    font-family: Work Sans-Regular, sans-serif;
}

.step1 {
    margin-bottom: 5%;
}

p.small_text {
    margin-top: 1%;
    margin-left: 1%;
    font-size: 11px;
    font-family: Work Sans-Regular, sans-serif;

}

/* efficacy_para */
.mobile-efficay-safety {
    display: none;
}

.efficacy_paragraph {
    padding-right: 5%;
    padding-left: 5%;
    text-align: center;
    font-size: 20px;
    margin-bottom: 5%;
}

.efficacy_paragraph p.text_purple {
    font-size: 20px;
    line-height: 23px;
    font-family: Work Sans-SemiBold, sans-serif;
}

/* four_boxes */
.four_boxes {
    background: url(../images/Rectangle.png) 1.3% 0% no-repeat padding-box;
    opacity: 1;
    padding-bottom: 4%;
    padding-left: 5.3%;
    background-size: cover;
}

.four_boxes .four-boxes-wrapper {
    display: flex;
}

.four_boxes .doising_information_l_para.four-box-desc {
    color: white;
    text-align: left;
    margin: 20px 32px 0 0;
}

.four_box_content.text_fourteen.Individualized-mobile {
    display: none;
}

.four_box_content.text_fourteen.minute-mobile {
    display: none;
}

.four_box_content.text_fourteen.mobile {
    display: none;
}

.box_one {
    width: 24%;
    text-align: center;
    padding: 0px 7px;
    margin-top: -2%;
}

.four_box_content {
    color: #ffffff;

}

/* footer */
.footer {
    padding-top: 2%;
    padding-bottom: 2%;
    margin-top: 5%;
    border-top: 2px solid #e50f63;
}
.pdf_link_footer{
    color: #2D2927;
}

.footer_content {
    display: flex;
    font-size: 11px;
    color: #000000;
    padding-left: 0;
    justify-content: space-around;
}

.footer_content p {
    font-family: Arial-Regular, sans-serif !important;
}

p.footer-middle-first {
    font-size: 13px;
    line-height: 15px;
    margin-bottom: 4%;
    color: #000000;
}

.fuse_code {
    font-size: 12px;
    line-height: 18px;
}

.footer .logo {
    max-width: 250px;
}

img.logo-image {
    width: 100%;
}

/* .footer_middle p,
.fuse_code p {
    margin-bottom: 3px;
} */

.fuse_code p {
    text-align: right;
}

.header_content_content {
    width: 100%;
}

/* calculator */
.purple-circle {
    background: url(../images/Button_Purple.png) 33% 100% no-repeat padding-box;
    background-size: cover;
    border-left: 1px solid;
    border-right: none;
}
.one_vial {
    color: #fff;
    margin-bottom: 20px;
    font-family: Work Sans-SemiBold, sans-serif;
    text-align: center;
    line-height: 17px;
}
.triangle.purple-triangle {
    content: '';
    display: block;
    position: absolute;
    border-left: 1px solid white;
    border-top: 1px solid white;
    border-bottom: 1px solid transparent;
    transform: rotate(140deg) skew(-10deg, -20deg);
    left: 18px;
    height: 24px;
    width: 24px;
}

.dosing-calc {
    max-width: 100%;
    margin: 30px 0;
    background: url(../images/Rectangle_color.svg) 0% 0% no-repeat padding-box;
    background-size: cover;
}

.calculate-button.btn {
    font-family: Work Sans-SemiBold, sans-serif;
    background: url(../images/Button_Purple.png) 85% no-repeat padding-box;
    background-size: 500px 44px;
    border: 1px solid white;
    border-bottom: 1px solid gray;
}

.calculator-title {
    color: #fff;
    font-family: Work Sans-SemiBold, sans-serif;
    padding-top: 24px;
}

.calc-inall-wrapper {
    text-align: center;
    margin: 0 22%;
}

.lbs-kq-wrapper {
    justify-content: space-evenly;
}

.radio-btn-wrapper {
    justify-content: space-evenly;
    padding-left: 14px;
}

.lbs-kq-wrapper,
.radio-btn-wrapper {
    display: flex;
    align-items: center;
    z-index: 1;
}

.error-border .lbs-kq-wrapper,
.error-border .radio-btn-wrapper {
    box-shadow: 0 0 0 4px white;
}

.lbs-kq-wrapper,
.radio-btn-wrapper {
    background: #fff;
    border-radius: 0 25px 25px 0;
    border: 1px solid #e50f63;
    height: auto;
    min-height: 44px;
    min-width: 100%;
}

.weight-wrapper,
.dose-wrapper {
    margin: 16px 0;
    display: flex;
    align-items: center;
    max-height: 54px;
}

.input-wrap {
    max-height: 30px;
}

.input-wrap input {
    border: none;
    outline: none;
    text-align: center;
    max-width: 48px;
    min-width: 48px;
    font-size: 16px;
    font-family: Work Sans-Regular, sans-serif;
}

.input-wrap #lb-input::placeholder,
.input-wrap #kg-input::placeholder {
    color: #582c5f;
}

.input-wrap.lb-wrap::after {
    content: "lb";
    display: none;
}
.input-wrap.kg-wrap::after {
    content: "kg";
    display: none;
}
.input-wrap.lb-wrap.show-after::after,
.input-wrap.kg-wrap.show-after::after {
    display: inline-block;
    font-family: Work Sans-Regular, sans-serif;
    position: relative;
    left: -4px;
}

.radio-wrap input[type=radio] {
    text-align: center;
    margin-right: 4px;
    transform: scale(2);
    cursor: pointer;
    appearance: none;
    -webkit-appearance: none;
    -moz-appearance: none;
    width: 14px;
    height: 14px;
    border-radius: 50%;
    border: 1px solid rgb(0, 0, 0);
    outline: none;
}

.radio-wrap input[type="radio"]:checked {
    background-color: #fff;
}

.radio-wrap input[type="radio"]:checked::before {
    content: "";
    display: block;
    width: 10px;
    height: 10px;
    border-radius: 50%;
    background-color: #E50F63;
    margin: 1px;
}


.radio-wrap input[type=radio]:checked+label {
    font-weight: bold;
}

.radio-wrap label {
    margin: 0 6px;
    font-size: 14px;
    cursor: pointer;
    font-family: Work Sans-Regular, sans-serif;
}

.radio-wrap:hover {
    font-weight: 700;
}

.lbs-kq-wrapper span.divider {
    border: 1px solid #e50f63;
    height: 24px;
}

.icon {
    display: flex;
    align-items: center;
    width: 48px;
    height: 44px;
    position: absolute;
    margin-left: -28px;
}

.error-border .icon {
    box-shadow: 0 0 0 4px white;
    border-radius: 50%;
}

.circle {
    background-color: #E50F63;
    display: flex;
    justify-content: center;
    align-items: center;
    font-size: 18px;
    font-family: Work Sans-SemiBold, sans-serif;
    color: #ffffff;
    padding-left: 10px;
    width: 30px;
    height: 44px;
    border-radius: 50px 0 0 50px;
    z-index: 2;
}

.triangle {
    width: 40%;
    height: 0;
    border-top: 22px solid transparent;
    border-bottom: 22px solid transparent;
    border-left: 14px solid #E50F63;
    position: absolute;
    left: 30px;
    z-index: 2;
}

p.cal_last_para {
    font-family: Work Sans-Medium, sans-serif;
    padding-left: 9%;
    padding-right: 9%;
    font-size: 20px;
    padding-bottom: 2%;
    text-align: center;
    color: #ffffff;

}
p.cal_last_paraa {
    font-family: Work Sans-Medium, sans-serif;
    font-size: 20px;
    padding: 0 9% 5% 9%;
    text-align: center;
    color: #ffffff;
}

strong.loading_dose {
    font-family: Work Sans-Bold, sans-serif;
    /* font-size: 20px; */
}

.calculate-button {
    font-weight: bold;
    text-align: center;
    color: #fff;
    margin: auto;
    background: #fff;
    border-radius: 0 25px 25px 0;
    height: auto;
    min-height: 44px;
    min-width: 100%;
    /* border-top: 1px solid #fff; */
    cursor: pointer;
    width: 100%;
}

.calculate-button:hover,
.calculate-button:active {
    font-size: 18px;
    color: #FFF;
    font-family: Work Sans-SemiBold, sans-serif;
}

.calc-outall-wrapper {
    display: flex;
    justify-content: space-between;
    padding: 20px 20px 36px 20px;
    align-items: flex-end;
}

.output-label {
    color: #fff;
    margin-bottom: 9px;
    font-family: Work Sans-SemiBold, sans-serif;
    /* font-weight: bold; */
    padding-left: 12px;
    line-height: 17px;
}

.out-wrap .output {
    background: #fff;
    border-radius: 25px;
    border: 1px solid #e50f63;
    height: auto;
    min-height: 44px;
    font-weight: bold;
    text-align: center;
    padding-top: 8px;
}

.out-wrap {
    flex: 1;
    padding: 0 14px;
}

.error-kg-msg,
.error-dose-msg {
    display: none;
    font-weight: bold;
    color: rgb(255, 255, 255);
    text-align: left;
    line-height: 18px;
}

.error-kg-msg {
    padding-top: 20px;
}

.error-kg-msg span.error-arrow,
.error-dose-msg span.error-arrow {
    content: "";
    border-top: 40px solid transparent;
    border-bottom: 40px solid transparent;
    border-right: 14px solid white;
    display: block;
    max-width: 20px;
    position: absolute;
    margin-left: 8px;
}

.error-kg-msg p,
.error-dose-msg p {
    margin-left: 30px;
    min-width: 100px;
    font-family: Work Sans-SemiBold, sans-serif;
}


.error-vol-msg {
    position: relative;
    padding-bottom: 8px;
}

.error-vol-msg p {
    font-weight: bold;
    color: rgb(255, 255, 255);
    text-align: left;
    line-height: 18px;
    font-size: 0.8rem;
    padding: 0 22px;
}

.error-vol-msg span.error-arrow {
    border-left: 50px solid transparent;
    border-right: 50px solid transparent;
    border-bottom: 16px solid white;
    border-top: none;
    display: inline-block;
    position: absolute;
    max-width: 20px;
    right: 10%;
    top: -24px;
}

/* Mobile */
@media only screen and (max-width: 1200px) {

    p.header_main_para {
        font-size: 49px;
    }
    
    .input-wrap input {
        max-width: 56px !important;
    }

    .Us-healthcare.text-white {
        margin-right: 4%;
    }

    .bookmark.dekstop {
        margin-left: 0;
    }

    li.nav-item.sp.sec {
        width: 15%;
    }

    .footer_middle {
        margin-left: 5%;
    }

    .twelve-resolution {
        display: block;
    }

    .before-twelve-resolution {
        display: none;
    }

}

@media only screen and (max-width: 992px) {
    span.patient {
        font-size: 13px;
    }
    .first_only {
        font-size: 15px;
    }
    .header_dekstop {
        margin-top: 5%;
    }

    .bookmark.dekstop {
        margin-left: -70px;
    }

    .arrow_ic {
        display: block;
        margin-left: 4%;
    }

    .col-lg-8.col-md-12.col-sm-12.three-links.left-sidebar {
        margin-bottom: 3px;
    }

    p.small_text {
        margin-left: 2%;
    }

    .box_one {
        padding: 0 4px;
    }

    li.nav-item.sp.sec {
        width: 100%;
    }

    .bg-brand {

        position: fixed;
        height: 56px;
        z-index: 10;

    }

    span.border_sp {
        height: 108px;

    }

    a.nav-link.text-white.underline {

        font-size: 26px;
        line-height: 40px;
        font-family: Arial-Regular, sans-serif;

    }

    p.header_main_para {
        font-size: 38px;
    }

    p.header_para {
        text-align: center;
        margin-left: 1%;
        margin-top: 0%;
        font-size: 15px;
    }

    li.DAI-links-li {
        text-align: center;
        background-color: #FCF9F9;
    }

    .header_logo img.top-banner-dekstop-image {
        width: 201px;
    }

    .icon-text {
        padding-right: 2%;
        padding-left: 2%;
        justify-content: center;
    }

    .h_image {
        padding-top: 2%;
    }

    .paddinG {
        padding-top: 8%;
    }

    .border_spp {
        border: 1px solid #ffffff;
        width: 86%;
        margin: 0 auto;

    }

    .efficacy_paragraph {
        width: 100%;

    }

    .navbar-collapse {
        height: auto;
        position: fixed;
        margin-top: 2%;

        width: 100vw;
        background: linear-gradient(206deg, #582c5f, #E50F63);
        z-index: 5;
        top: 38px;
        left: 0px;
        padding: 0px 30px;
    }

    ul.navbar-nav {
        font-size: 24px;
        padding-top: 39px;
    }

    .last_pr {
        display: none;
    }

    img.logo-image {
        width: 40%;
    }

    .footer_middle {
        margin-top: 5%;
        margin-bottom: 5%;

    }

    .header_Mobile {
        display: none;

    }

    .fuse_code p {
        text-align: left;
    }

    .footer_content {
        padding-left: 60px;
        display: block;

    }

    .footer_middle,
    .fuse_code {
        margin-left: 63px;
    }

    .footer_content {
        padding-left: 25px;
    }

    .footer_middle p {
        margin-bottom: 13px;
    }

    p.fuse-middle {
        margin-bottom: 2%;
    }

    img.logo-image {
        width: 100%;
    }
}

@media only screen and (max-width: 768px) {
    .mobile-efficay-safety {
        display: block;
    }
    /* p.j_ref.sec {
        margin-bottom: 1rem;
    } */
    /* .j_code_text.j_mobile {
        margin-top: 14%;
    } */
    p.para_jcode.text_purple.bt_d.parmanent_jcode.mr_t {
        margin-bottom: 3%;
    }
    .one_vial{
        padding: 0 60px;
    }
    ul.DAI-links {
        max-width: 100%;
    }
    .dekstop-efficay-safety {
        display: none;
    }

    .header_Mobile {
        display: block;
        margin-top: 6%;

    }

    .four_box_content.text_fourteen.minute-mobile,
    .mobile-single-use {
        display: block;
    }

    .four_box_content.text_fourteen.minute-dekstop,
    .dekstop-single-use {
        display: none;
    }

    .navbar {
        padding-top: 0.2rem;
    }

    p.bookmark {
        line-height: 16px;
        font-size: 16px;
    }

    .footer {
        padding-top: 5%;
    }

    li.nav-item.sp {
        align-items: baseline !important;
    }

    .nav-item.sp.t a {
        max-width: 335px;
    }

    .nav-item.sp.t i {
        margin-left: 12px !important;
    }

    .footer_middle {
        margin-top: 8%;
        margin-bottom: 8%;
    }

    .h_imageM {

        padding-top: 3%;
    }

    p.header_main_para {
        font-size: 54px;
    }

    p.header_main_para.info {
        padding-left: 23%;
        margin-top: -7%;
    }

    label.accordion {
        border-radius: 43px;
        color: #FFF;
        font-size: 15px;
    }

    .header_dekstop {
        display: none;
    }

    .top-banner-mobile-image {
        display: block;
    }

    .header_logo {
        padding-left: 15%;
        margin-bottom: 3%;
    }

    .header_logo img.top-banner-dekstop-image {
        width: 333px;
    }

    .header_content {
        padding-left: 20%;
    }
}

/*  calcualtor responsives*/

@media only screen and (max-width: 768px) {
    .calc-inall-wrapper {
        /* margin: 0px auto; */
        max-width: calc(100vw - 100px);
    }

    .bookmark.mobile {
        margin-left: -12%;
        display: flex !important;
        align-items: center;
    }

    .bookmark.dekstop,
    .Us-healthcare.text-white.dekstop {
        display: none;
    }

    .bookmark.mobile,
    .Us-healthcare.text-white.mobile {
        display: block;
    }

    .arrow_ic {
        margin-left: 6%;
    }

    img.arrow_ic.first {
        margin-left: 1%;
    }

    .calc-inall-wrapper {
        margin: 0% 10%;
    }

    .icon {
        margin-left: -8px;
    }

    .radio-wrap label {
        max-width: 40px;
        text-align: left;
        line-height: 16px;
    }

    .radio-btn-wrapper {
        padding: 0 24px;
    }

    .radio-wrap {
        display: flex;
        align-items: center;
    }

    .weight-wrapper,
    .dose-wrapper {
        margin: 24px 0;
        display: block;
        height: auto;
        max-height: none;
    }

    .calc-outall-wrapper {
        display: block;
    }

    .output-label {
        margin: 18px 0 4px 0;
    }

    .error-kg-msg span.error-arrow,
    .error-dose-msg span.error-arrow {
        border-left: 50px solid transparent;
        border-right: 50px solid transparent;
        border-bottom: 16px solid white;
        border-top: none;
        display: block;
        position: relative;
        margin: auto;
    }

    .error-kg-msg p,
    .error-dose-msg p {
        margin-left: 0;
        text-align: center;
        padding-top: 10px;
    }

    .lbs-kq-wrapper,
    .radio-btn-wrapper,
    .calculate-button {
        border-radius: 25px;
        position: relative;
    }

    .error-dose-msg {
        margin-top: 14px;
    }

    .error-vol-msg span.error-arrow {
        display: block;
        position: relative;
        margin: auto;
        right: unset;
        top: -20px;
    }
    .it_video {
        text-align: center;
    }
    .instructional_video {
        display: block;
    }
    .instructional_video .it_video iframe {
        width: 220px;
        height: 126px;
    }
    .instructional_video .it_text {
        padding-right: 0;
    }
}

@media screen and (max-width: 540px) {
    .nav-item.sp.t a {
        max-width: 188px;
    }
    .last_paragraph {
    margin-top: 5%;
}
.location-iconText {
    margin-bottom: 2%;
}
    /* .j_code_text.j_mobile {
        margin-top: 16%;
    } */
    .navbar {
        padding-top: 5px;
    }
    .header_Mobile {
        margin-top: 10%;

    }

    .four_box_content.text_fourteen.dekstop {
        display: none;
    }

    .four_box_content.text_fourteen.mobile {
        display: block;
    }

    .four_box_content.text_fourteen.Individualized-mobile {
        display: block;
    }

    .four_box_content.text_fourteen.Individualized-dekstop {
        display: none;
    }

    p.bookmark {
        font-size: 15px;
        margin-left: 3px;
    }

    .bookmark.mobile {
        margin-left: -32px;
    }

    p.consentex-solution {
        /* padding-left: 5%;
        padding-right: 5%; */
        color: #000000;
    }

    img.arrow_ic.first {
        margin-left: 2%;
    }

    .arrow_ic {
        margin-left: 13%;
    }

    .footer {
        padding-top: 7%;
    }

    .icon-text {
        padding-left: 13%;
        justify-content: left;

    }

    .icon-text-main {
        display: block;

    }

    table.dosing-table th {
        font-size: 10px;
    }

    table.dosing-table td {
        font-size: 14px;
    }

    .four_boxes_mobile {
        display: block;
        background: url(../images/Rectangle@2x.png) 0% 0% no-repeat padding-box;
        opacity: 1;
        height: auto;
        padding-left: 6%;
    }
    .four_boxes_mobile .four-boxes-wrapper {
        display: block;
    }
    .four_boxes .doising_information_l_para.four-box-desc {
        margin-left: 32px;
    }
    .header_logo img.top-banner-dekstop-image {
        width: 257px;
    }

    .header_content {
        padding-left: 12%;

        padding-right: 10%;
    }

    .header_logo {
        padding-left: 13%;
        padding-right: 10%;
    }

    .box_one {
        text-align: center;
        width: 80%;
        margin: 0 auto;
        margin-top: 6%;
    }

    .four_boxes.four_boxes_mobile {
        padding: 0;
        margin-top: 11%;
        padding-bottom: 5%;
    }

    img.top-banner-image.first_box_mobile {
        margin-top: -6%;
    }

}

@media screen and (max-width: 390px) {
  
    .Bookmark.text-white,
    .Us-healthcare.text-white {
        margin-right: 2%;
        margin-left: -2%;
    }
    .header_Mobile {
        margin-top: 15% !important;

    }
    .bookmark.mobile {
        margin-left: -11px;

    }

    table.dosing-table th {
        font-size: 10px;
        padding: 7px 2px 15px 10px;
    }
}

/*  calcualtor responsives*/
@media only screen and (min-width: 679px) and (max-width: 1199px) {
    .calc-inall-wrapper {
        margin: 0% 18%;
    }
}

@media only screen and (max-width: 381px) {
    label.accordion::after {

        font-size: 16px;

        margin-top: -9px;


    }
}

@media only screen and (max-width: 494px) {
    label.accordion::after {
        margin-top: -10px;
    }
    .header_Mobile {
        margin-top: 11%;

    }
    /* .j_code_text.j_mobile {
        margin-top: 20%;
    } */
    label.accordion {
        padding-right: 10%;
        padding-left: 10%;
    }

    p.header_main_para.info {
        padding-left: 16%;
        margin-top: -7%;
    }

    p.header_main_para {
        font-size: 46px;
    }

    .footer_middle {
        margin-top: 9%;
        margin-bottom: 11%;
    }
}

@media only screen and (min-width: 1400px) {
    .bookmark.dekstop {
        margin-left: 7%;
    }
}

@media only screen and (min-width: 768px) and (max-width: 1199px) {
    .calc-inall-wrapper {
        margin: 0% 22%;
    }
}

@media only screen and (min-width: 992px) and (max-width: 1200px) {
    .efficacy_paragraph p.text_purple {
        font-size: 19px;
    }
}

@media only screen and (min-width: 768px) and (max-width: 768px) {
    .container {
        max-width: 560px;
    }

    label.accordion {
        font-size: 17px !important;
    }
}

@media only screen and (min-width: 490px) and (max-width: 768px) {
    label.accordion {
        font-size: 16px;
    }

    label.accordion::after {
        margin-top: 0;
    }
}

@media only screen and (min-width: 549px) and (max-width: 575px) {
    label.accordion {
        font-size: 16px;
    }
}

@media only screen and (max-width: 545px) {
    label.accordion {
        padding-right: 60px;
    }
    label.accordion::after {
        margin-top: -10px;
    }
}